MENewman Dr. Michael Ezra Newman, Ph.D.

[CV taken from Hadassah website]

Date of birth: 11 November 1949 (Sheffield, U.K.)

Married, 3 children

Academic Background

1968-71  Cambridge University , U.K. ( Sidney Sussex College ) Natural Sciences Tripos.  

v        Part 1A [Chemistry, Physiology, Biology of Cells]  grade II

v        Part IB [Biochemistry, Physiology, Pathology] grade II(1)

v        Part II [Biochemistry]    grade II(1)

1971-74   London University , U.K. ( Imperial College )

Research in Biochemistry for Ph.D. degree. Subject of Thesis: "Insulin and glucagon in lean and genetically obese mice"

Positions held

1975-79  Research Worker in Biochemistry at Institute of Psychiatry, de Crespigny Park, Denmark Hill, London, U.K.

1980-81  Post-doctoral Fellow, Hebrew University of Jerusalem , Israel (Department of Biological Chemistry, Institute of Life Sciences )

1982-91  Senior Research Scientist, Jerusalem Mental Health Centre, Ezrath Nashim Hospital , Jerusalem , Israel

1992 - Senior Scientist, Biological Psychiatry Laboratory, Dept. of Psychiatry, Hadassah University Hospital , Jerusalem , Israel .

Grant Support

1987-88 Israel Institute for Psychobiology (Charles E. Smith Foundation) “Lithium and serotonergic function in rat brain”

1987-91 National Institutes of Health , U.S.A. “Serotonergic mechanism of action of antidepressants” (Principal Investigator)

1993-95 Stanley Foundation Research Awards Program. “Use of microdialysis to determine the effects of antidepressants on second messenger  responses in the living rat"

1994-97 Israel Institute for Psychobiology (Charles E. Smith Foundation) " Mechanism of 5-HT-1a receptor agonist action in the rat brain"

1994-97 Milton Rosenbaum Endowment Fund for Research in Psychiatric Science.  "Use of microdialysis to determine the effects of antidepressants on serotonin and cyclic AMP levels in the living rat"

1995 - Joint research fund of Hadassah and the Hebrew University "Use of microdialysis to determine the effect of lithium on inositol trisphosphate formation in rat brain"

1997-2000  U.S. - Israel Binational Science Foundation “Effects of antidepressants on 5-HT-1a receptor functioning in vivo in the rat brain”

2000-2003 Israel Science Foundation “Role of serotonin 5-HT1a receptors in the potentiation of antidepressant action by triiodothyronine”

Chief Scientist, Israel Ministry of Health “Effect of early maternal deprivation on the serotonergic system in rat brain"

National Institutes of Health, U.S.A.”Basic mechanisms of antidepressant potentiation”

National Institutes of Health, U.S.A (Fogarty International Research Co-operation Award) “Time Course and Potentiation of Fluoxetine Action”

Society Memberships

v        Collegium Internationale Neuro-Psychopharmalogicum

v        Israel Society for Physiology and Pharmacology

v        Israel Society of Biological Psychiatry

v        Serotonin Club

v        Society for Neuroscience

Consultant Activities

Grant Reviewer 

v        U.S.-Israel Binational Science Foundation

v        German-Israel Foundation for Scientific Research and Development

v        Chief Scientist’s Office, Israel Ministry of Health

v        Israel Science Foundation

v        Israel Ministry of Science

v        National Institute for Psychobiology in Israel

v        Israel Authority against Drug Abuse

Journal Reviewer

v        Biological Psychiatry

v        European Journal of Pharmacology

v        International Journal of Neuropsychopharmacology

v        Journal of Neural Transmission

v        Journal of Neurochemistry

v        Journal of Psychiatric Research

v        Life Sciences

v        Neurochemistry International

v        Neuropharmacology

v        Pharmacology and Toxicology

v        Psychiatry Research

v        Psychopharmacology

List of Publications

Beloff-Chain, A., Newman, M. E., Mansford K.L.M.: In vitro studies on insulin secretion in the genetically obses mouse. Diabetologia 9: 447-452 (1973)

Beloff-Chain, A., Newman, M. E., Mansford K.L.M.: Factors influencing insulin and glucagon secretion in lean and genetically obese mice. Hormone and Metabolic Research 9: 33-37 (1977)

Newman, M.E. : Glycogen metabolism and cyclic AMP levels in isolated islets of lean and genetically obese mice. Hormone and Metabolic Research 9: 358-361 (1977)

Newman, M., McIlwain, H. : Adenosine as a constituent of the brain and of isolated cerebral tissues, and its relationship to the generation of adenosine 3’:5”-cyclic monophosphate. Biochem. J. 164: 131-137 (1977)

Newman, M.E., McIlwain, H.: Cellular site and state of combination of the adenosine 3'5'-cyclic monophosphate persisting after excitation of cerebral tissues. Biochem J. 170: 73-79 (1978)

Traversa, U., Newman, M.E.: Stereospecific influence of oxazepam hemisuccinate on cyclic AMP accumulation elicited by adenosine in cerebral cortical slices. Biochem. Pharmacol. 28: 2363-2365 (1979)

Newman, M.E., Patel, J., McIlwain, H.: The binding of 3H-adenosine to synaptosomal and other preparations from the   mammalian brain. Biochem. J. 194: 611-620 (1981)

Patel, J., Newman, M.E., McIlwain, H.: Cyclic AMP binding capabilities and histone kinase activation insubcellular components of neocortical tissue: Differential responses to three neurohumoral agents.Biochem. J. 194: 621-626  (1981)

Newman, M.E., Levitzki, A.: Characteristics of high affinity (3H)adenosine binding to rat brain synaptosomes  and   turkey erythrocyte membranes. Biochem Biophys. Acta 685: 129-136 (1982)

Newman, M.E.: Relationship of the inhibition of epinephrine -stimulated adenylate cyclase in turkey erythrocytes  by  adenosine to its "R-site" and "P-site" mediated effects.  Biochem. Pharmacol 32: 37-40 (1983)

Newman, M.E., Levitzki, A.: Desensitization of normal rat kidney (NRK) cells to adenosine. Biochem. Pharmacol. 32: 137-140 (1983)

Newman, M.E.: Adenosine binding sites in brain: Relationship to endogenous levels of adenosine and to its  physiological and regulatory roles (Commentary).  Neurochem. Int. 5: 21-26 (1983)

Newman, M.E., Klein, A., Birmaher, B., Feinsod, M.,Belmaker, R.H.: Lithium at therapeutic concentrations inhibits human brain noradrenaline-sensitive cyclic AMP accumulation.  Brain Res. 278: 380-381 (1983).

Newman, M.E., Zohar, J., Kalian, M., Belmaker, R.H.: The effects of chronic lithium and ECT on A1 and  A2 adenosine receptor systems in rat brain. Brain Res. 291: 188-192 (1984).

Klein, E., Lerer, B., Newman, M.E., Belmaker, R.H., Bhargava, H.N.: The effect of cyclo (leu-gly) on reserpine-induced hypomotility and increases in  cortical beta-adrenergic receptors.  Psychopharmacology 83: 76-78 (1984)

Shapira, B., Zohar, J., Newman, M., Drexler, H., Belmaker, R.H.: Potentiation of seizure length and clinical response to electroconvulsive therapy by caffeine pretreatment: a case report. Convulsive Therapy 1: 58-60 (1985)

Newman, M.E.: Adenosine-homocysteine interactions in controlling cyclic AMP in rat brain cortical slices. Biochem. Pharmacol. 34: 1435-1438 (1985)

Hamburger, R., Newman, M.E.: Effects of vasopressin on noradrenalin induced cyclic AMP accumulation in rat brain slices. Pharmacol. Biochem. Behav. 22: 183-187 (1985).

Newman, M.E., Lichtenberg, P., Belmaker, R.H.: Effects of lithium in vitro on noradrenaline-induced cyclic AMP accumulation in  rat cortical slices after reserpine-induced supersensitivity. Neuropharmacology 24:353-355  (1985)

Newman, M.E.: Vasopressin inhibits cyclic AMP accumulation and adenylate cyclase activity in cerebral preparations. FEBS Letters 181: 203-206 (1985)

Newman, M.E., Hamburger, R.: Vasopressin inhibition of cyclic AMP accumulation and effects on the learned response in inbred mouse  strains. Life Sciences 37: 2037-2042 (1985)

Hamburger, R., Robert, M., Newman, M.E, Belmaker, R.H.: Interstrain correlation between behavioural effects of lithium and effects on cortical cyclic AMP. Pharmacol. Biochem. Behav. 24: 9-13 (1986)

Newman, M.E., Solomon, H., Lerer, B.: Electroconvulsive shock and cyclic AMP signal transduction:effects distal to  the receptor. J. Neurochem. 46: 1667-1669 (1986)

Newman, M.E and Belmaker, R.H.: Effects of lithium in vitro and ex vivo on components of the adenylate cyclase system in rat cerebral cortex membranes. Neuropharmacology 26: 211-217  (1987).

Newman, M.E., Lipot, M., Lerer, B.: Differential effects of chronic desipramine administration on the cyclic AMP response in rat cortical slices and membranes. Neuropharmacology 26: 1127‑1130 (1987).

Newman, M.E., Miskin, I., Lerer, B.: Effects of single and repeated electroconvulsive shock administration on inositol  phosphate accumulation in rat brain slices. J. Neurochem. 49: 19‑23 (1987).

Newman, M.E. and Lerer, B.: Effects of lithium and desipramine administration on inositol phosphate accumulation in rat cerebral cortex. Biochem. Pharmacol. 37: 1991‑1995 (1988).

Newman, M.E. and Lerer, B.: Chronic electroconvulsive shock and desipramine  reduce the degree of inhibition by 5‑HT and carbachol of forskolin‑stimulated adenylate cyclase in rat hippocampal membranes. Eur. J.Pharmacol. 148: 257‑260 (1988).

:

Ebstein RP, Lerer B, Bennett ER, Dayek DB, Newman ME, Shapira B, Kindler S.  Second messenger function in lymphocytes and platelets: a comparison of peripheral and central mechanisms.  Clin Neuropharmacol. 1986;9 Suppl 4:350-2

Newman, M.E. and Lerer, B.: Modulation of second messenger function in rat brain by in vivo alteration of receptor sensitivity: Relevance to mechanism of action of electroconvulsive therapy and antidepressants. Prog. Neuropsychopharmacol. Biol. Psych. 13: 1-30 (1989).

Newman, M.E. and Lerer, B.: Post‑receptor mediated increases in adenylate cyclase activity after chronic antidepressant treatment: Relationship to receptor desensitisation. Eur. J. Pharmacol.162: 345-352 (1989).

Newman, M.E. and Lerer, B.: Effects of chronic ECS on D1 and D2 dopamine receptor‑mediated adenylate cyclase  activity in rat striatal and limbic forebrain homogenates   Neuropharmacology 28: 787-790 (1989).

Newman, M.E., Drummer, D., Lerer, B.: Single and  combined effects of desipramine and  lithium on serotonergic receptor number and second messenger function in rat brain.  J.  Pharmacol. Exptl. Ther. 252: 826-238  (1990).

Shoham, S., Newman, M.E., Wurtman, E. and Ebstein, R.P.: Cholinergic second messenger systems after  nucleus  basalis lesions in rat brain: Presynaptic deficit correlates with memory loss. Pharmacol. Biochem. Behav. 36: 507- 513 (1990).

Kofman, O., Klein, E., Newman., M.E., Hamburger, R., Kimche,O., Nir, T., Shimon, H., Belmaker, R.H. Inhibition by antibiotic tetracyclines of rat cortical noradrenergic adenylate  cyclase and amphetamine-induced hyperactivity. Pharmacol. Biochem. Behav. 37: 417-424  (1990)

Newman, M.E., Lerer, B.: 5HT-1A receptor-mediated effects of antidepressants: Relation to G  protein function. Clin Neuropharmacol. 13: (Suppl. 2) 237-238 (1990).

Belmaker, R.H., Lerer, B., Newman, M.E., Fuchs, I.: Lack of effect of lithium, propranolol or haloperidol on basal plasma cyclic AMP levels. Lithium, 2: 115-116 (1991)

Newman, M.E.: Lithium and the phosphoinositide hydrolysis second messenger system: a critical review of its therapeutic relevance. Lithium, 2: 187-194 (1991)

Newman, M.E., Ben-Zeev, A., Lerer, B.: Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate  cyclase in rat hippocampus. Eur. J.Pharmacol.,   207: 209-213 (1991)

Newman, M.E., Shapira, B., Lerer, B.: Effects of lithium and desimipramine on second messenger responses in rat hippocampus: relation to G protein effects. Neuropharmacology,  30: 1297-1301 (1991)

Rogel-Fuchs, Y., Newman, M.E., Trombka, D., Zahalka, E.A.,Yanai, J.: Hippocampal cholinergic alterations and related behavioral deficits after early exposure to phenobarbital.  Brain Res. Bulletin, 29: 1-6 (1992)

Newman, M.E., Shapira, B., Lerer, B.: Regulation of 5-HT-1a receptor function in rat hippocampus by short- and long-term administration of 5-HT-1a agonists and antidepressants. J. Pharmacol. Exptl. Ther., 260: 16-20 (1992)

Shapira, B., Yagmur, M., Gropp, C., Newman, M.E., Lerer, B.: Effect of clomipramine and lithium on fenfluramine-induced hormone release in major depression. Biol. Psychiat., 31: 975-983 (1992)

Newman, M.E.: Serotonin inhibits adenylate cyclase in human platelet membranes. Eur.J. Pharmacol. 226: 281-285 (1992)

Newman, M. E., Lerer, B., Lichtenberg, P., Shapira, B.: Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function. Psychopharmacology, 109: 231-234 (1992)

Lichtenberg, P., Shapira, B., Gillon, D., Kindler, S., Cooper, T.B., Newman, M.E., Lerer, B.:Hormone responses to fenfluramine and placebo challenge in endogenous depression. Psychiatry Research, 43: 137-146 (1992)

Shapira, B., Newman, M.E., Lerer, B.: Serotonergic mechanisms of ECT: Neuroendocrine evidence. Clin. Neuropharmacol. 15: (Suppl. 1) 673A-674A (1992)

Yanai, J., Rogel-Fuchs, Y., Pick, C.G., Slotkin, T., Seidler, F.J., Zahalka, E.A., Newman, M.E.: Septohippocampal cholinergic changes after destruction of the A10-septal dopaminergic pathways.  Neuropharmacology, 32: 113-118 (1993)

Newman, M. E., Lerer, B., Shapira, B.: 5-HT-1a receptor-mediated effects of antidepressants.  Prog. Neuropsychopharmacol. Biol. Psychiat., 17: 1-19 (1993)

Shapira, B., Cohen, J., Newman, M.E., Lerer, B.: Prolactin response to fenfluramine and placebo challenge following maintenance pharmacotherapy withdrawal in remitted depressed patients. Biol. Psychiat., 33: 531-535 (1993)

Shapira, B., Newman, M.E., Lerer, B.: Serotonergic mechanisms in depression: clinical insights and biological correlates. Israel J. Med. Sci., 30: 162-167 (1994)

Weizman, R., Gur, E., Laor, N., Reiss, A., Muller, U., Yoresh, A., Lerer, B., Newman, M.E.: Platelet adenylate cyclase activity in Israeli victims of Iraqi Scud missile attacks with post traumatic  stress disorder. Psychopharmacology, 114: 509-512 (1994)

Gur, E., Rogel-Fuchs, Y., Newman, M.E., Lerer, B.: Effects of antidepressants on cyclic AMP responses in the living rat. Eur. Neuropsychopharmacol. 4: 317 (1994)

Segman, R., Newman, M.E., Lerer, B.: Serotonin stimulation of GTP binding in rat hippocampal membranes and the action of antidepressant drugs. Eur. Neuropsychopharmacol.  4: 318 (1994)

Newman, M.E.: Serotonin inhibition of adenylate cyclase in human platelet membranes; relation to 5-HT-1a receptor -mediated activity. Biochem.Pharmacol., 48: 1677-1682 (1994)

Lesch, K.P., Stober, G., Balling, U., Franzek, E., Li, S.H., Ross, C., Newman, M.E.,  Beckmann, H.  Riederer, P.(1994) Triplet repeats in clinical subtypes of schizophrenia: variation at  the DRPLA (B37 CAG repeat) locus is not associated with periodic catatonia. J. Neural Transm. 98: 153-158 (1994)

Kohn, Y., Newman, M.E., Lerer, B., Orr, S.P., Pitman, R.K.: Absence of reduced platelet adenylate cyclase activity in Vietnam veterans with PTSD. Biol. Psychiat., 37: 205-208 (1995)

Zahalka, E.A., Rehavi, M., Newman, M.E., Yanai, J.:  Alterations in hippocampal hemicholium-3 binding and related  behavioural and biochemical changes after prenatal  phenobarbital exposure. Psychopharmacology, 122: 44-50 (1995)

Gur, E., Lerer, B., Newman, M.E.: Acute or chronic lithium does not affect agonist-stimulated inositol  trisphosphate formation in rat brain in vivo. NeuroReport, 7: 393-396  (1996)

Abu-Roumi, M., Newman, M.E., Yanai, J.: Inositol phosphate formation in mice prenatally exposed to drugs:  relation to muscarinic receptors and post-receptor effects.  Brain Res. Bulletin, 40: 183-186 (1996)

Gur, E., Berman, E., Lerer, B., Newman, M.E.: In vivo cyclic AMP responses in rat brain are not modified by chronic electroconvulsive shock. Eur. Neuropsychopharmacol., 7: 189-193 (1997)

Gur, E., Lerer, B., Newman, M.E.: Chronic electroconvulsive shock and 5-HT autoreceptor activity in rat brain; an in vivo microdialysis study. J. Neural Transm., 104: 795-804 (1997)

Newman, M.E., Gur, E., Shapira, B., Lerer, B.: Neurochemical mechanisms of action of ECS: evidence from in vivo studies. Journal of ECT Research, 14: 153-171 (1998)

Newman, M.E., Shapira, B., Lerer, B.: Evaluation of central serotonergic function in affective and related disorders by the fenfluramine challenge test: a critical review. Int. J. Neuropsychopharmacol., 1: 49-69 (1998)

Feldman, S., Newman, M.E., Weidenfeld, J.: Role of serotonin in the amygdala in hypothalamo-pituitary-adrenocortical responses. NeuroReport 9: 2007-2009 (1998)

Newman, M.E.: The need for cautiously extrapolating results obtained with normal animals (healthy individuals) to depressed ones (Matters Arising-letter). J. Neurochem. 70: 2641 (1998)

Gur, E., Lerer, B., Newman, M.E.: Chronic clomipramine and triiodothyronine increase 5 HT levels in rat frontal cortex in vivo: relationship to 5-HT autoreceptor activity. J Pharmacol. Exp. Ther. 288: 81-87 (1999)

Lerer B., Gelfin Y., Gorfine M., Allolio B., Lesch K.P., Newman M.E:. 5-HT1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge. Neuropsychopharmacology, 20: 628-639 (1999)

Gur, E., Dremencov, E., Lerer, B., Newman, M.E.: Venlafaxine: acute and chronic effects on 5-HT levels in rat brain in vivo. Eur. J. Pharmacol., 372: 17-24 (1999)

Newman, M.E., Gelfin, Y., Li, Q., Van de Kar, L.D., Lerer, B.: Low doses of ipsapirone increase growth hormone but not oxytocin secretion in normal male and female subjects. Psychopharmacology, 145: 99-104 (1999)

Dremencov, E., Gur, E.,  Lerer, B., Newman, M.E: Subchronic fluoxetine administration to rats: effects on 5-HT autoreceptor activity as measured by in vivo microdialysis. Eur. Neuropsychopharmacol., 10: 229-236 (2000)

Shapira, B., Newman, M.E., Gelfin, Y., Lerer, B. :Blunted temperature and hormone responses to ipsapirone in major depression: lack of enhancement by electroconvulsive therapy.  Psychoneuroendocrinology, 25: 421-438 (2000).

Newman, M.E., Agid, O. Gur, E., Lerer, B. Pharmacological mechanisms of T3 augmentation of antidepressant action. Int. J. Neuropsychopharmacol., 3: 187-191 (2000)

Feldman, S., Newman, M.E., Weidenfeld, J. Effects of adrenergic and serotonergic agonists in the amygdala on the hypothalamo-pituitary-adrenocortical axis. Brain Res. Bulletin, 52: 531-536 (2000)

Gur, E., Lerer, B., Dremencov, E., Newman, M.E.: Chronic repetitive transcranial magnetic stimulation induces subsensitivity of presynaptic serotonergic autoreceptor activity in rat brain. Neuroreport, 11: 2925-2929 (2000).

Newman, M.E., Gur, E., Dremencov, E., Garcia, F., Lerer, B., van de Kar, L.D.: Chronic clomipramine alters presynaptic 5-HT1B  and postsynaptic 5-HT1A receptor sensitivity in rat hypothalamus and hippocampus respectively. Neuropharmacology, 39: 2309-2317 (2000)

Steingart, R.A., Abu-Roumi , M., Newman, M.E., Silverman, W.F., Slotkin, T.A., Yanai, J. Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: cellular mechanisms and the reversal of deficits by neural grafts. Brain Research Dev. Brain Res. 30: 125-133 (2000)

Gur, E., Dremencov, E., Lerer, B., Newman, M.E.: Functional  effects  of  corticosterone  on 5-HT1A  and  5-HT1B  receptor  activity  in  rat  brain: in  vivo  microdialysis  studies. Eur. J. Pharmacol., 411: 115-122 (2001)

Gur, E., Dremencov, E., van de Kar, L.D., Lerer, B., Newman, M.E.: Effects of chronically administered venlafaxine on serotonin receptor activity in rat hippocampus and hypothalamus. Eur. J. Pharmacol., 436: 57-65 (2002)

Weidenfeld, J., Feldman, S., Itzik, A., van de Kar, L.D., Newman, M.E. : Evidence for a mutual interaction between noradrenergic and serotonergic agonists in stimulation of ACTH and corticosterone secretion in the rat. Brain Res., 941: 113-117 (2002)

Gur, E., Dremencov, E., Garcia, F., van de Kar, L.D., Lerer, B., Newman, M.E.: Functional  effects  of  chronic  electroconvulsive  shock  on  serotonergic 5-HT1A  and  5-HT1B  receptor  activity  in  rat  hippocampus and  hypothalamus. Brain Res., 952: 52-60 (2002)

Dremencov, E., Gur, E., Lerer, B., Newman, M.E.: Effects of chronic antidepressants and electroconvulsive shock on serotonergic neurotransmission in the rat hypothalamus. Prog. Neuropsychopharmacol. Biol. Psychiat., 26: 1029-1034 (2002)

Weidenfeld, J., Newman, M.E., Itzik A., Gur, E., Feldman, S.: The amygdala regulates the pituitary-adrenocortical response and release of hypothalamic 5-HT following electrical stimulation of the dorsal raphe nuclei in the rat. Neuroendocrinology, 76: 63-69 (2002)

Gur, E., Lifschytz, T., Lerer, B., Newman, M.E.: Effects of triiodothyronine and imipramine on basal 5-HT levels and 5-HT1 autoreceptor activity in rat cortex. Eur. J. Pharmacol., 457: 37-43 (2002)

Gur, E., Lerer, B., Van de Kar, L.D., Newman, M.E.: Chronic rTMS induces subsensitivity of post-synaptic 5-HT1A receptors in rat hypothalamus. Submitted

Gur, E., Lifschytz, T., Van de Kar, L.D., Lerer, B., Newman, M.E.: Effects of triiodothyronine on 5-HT1A and 5-HT1B autoreceptor activity, and postsynaptic 5-HT1A receptor activity, in rat hypothalamus. Submitted

Dremencov, E., Gur, E., Lerer, B., Newman, M.E.: Effects of chronic antidepressants and electroconvulsive shock on serotonergic neurotransmission in the rat hippocampus. Prog. Neuropsychopharmacol. Biol. Psychiat.,

Gur, E., Newman, M.E., Avraham, Y., Dremencov, E., Berry, E.M.: The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats. Nutr. Neurosci., in press

Book Chapters

Newman, M.E., Patel J.: Protein binding of cyclic AMP in interpretation of its role in neural conduction. In: Chemisms of the Brain, eds. R. Rodnight, H.S. Bachelard, W.L. Stahl, Churchill Livingstone, pp. 130-135 (1981)

Newman, M.E.: Modulation of adenylate cyclase by physiological and pharmacological manipulation of the prevalent adenosine concentration. In: Purines: Pharmacology and Physiological Roles, ed. T.W.Stone, MacMillan, pp. 185-192 (1985)

Newman, M.E., Belmaker, R.H., Hamburger-Bar R., Lerer, B.: Receptor-mediated and –independent effects in the actions of lithium and electroconvulsive shock on adenylate cyclase. In: Drug Receptors and Dynamic Processes in Cells, eds. J.S.Schou, A. Geisler, S. Norn, Munksgaard, pp 290-301 (1986).

Newman, M.E., Lerer, B.: Changes in rat brain second messenger function on administration of psychoactive drugs: relationship to receptor number and desensitization. In: Progress in Catecholamine Research, Part B: Central aspects, eds. M.Sandler, A. Dahlstrom, R.H. Belmaker, A.R. Liss Inc. pp 389-395 (1988)

Lerer, B., Gur, E., Bleich, A., Newman, M.E.: Peripheral adrenergic receptors in PTSD. In: Catecholamine Function in Posttraumatic Stress Disorder, ed. M. Murburg, American Psychiatric Press, pp. 257-276 (1994)

Yirmiya, R., Pollak, Y., Morag, M., Reichenberg, A., Barak, O., Avitsur, R., Shavit, Y., Ovadia, H., Weidenfeld, J., Morag, A., Newman, M.E., Pollmacher, T.: Illness, Cytokines and Depression. In: Annals of the New York Academy of Sciences, Vol. 917, pp. 478-487 (2000)

Newman, M.E., Lerer, B.: Neurotransmitters and second messengers. In: New Oxford Textbook of Psychiatry, eds. M.G. Gelder, J.J. Lopez-Ibor, N.C. Andreasen, Oxford University Press, Vol. 1 pp. 188-197 (2001)

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